Top NFL bets often focus on key matchups, player performances, and betting trends. Popular wagers include point spreads, moneylines, and over/under totals, with savvy bettors analyzing team statistics, injuries, and weather conditions. Betting on underdogs can yield high returns, while favorites may offer safer options. Prop bets, such as player touchdowns or yardage, add excitement and variety. As the season progresses, staying informed about team dynamics and expert insights can enhance betting strategies, making each game an opportunity for potential profit.