Which online casino pays out the most can vary based on numerous factors including game selection, payout percentages, and bonuses offered. Players often seek casinos with high return-to-player (RTP) rates, as these can indicate better chances of winning over time. Some prominent online casinos are known for generous payouts and fair gaming practices. It is advisable for players to research and compare different casinos to find those that consistently offer the highest payouts. Always read reviews and check player testimonials to ensure a safe and rewarding gaming experience.