When it comes to casino games with the best payouts, players often gravitate towards blackjack, baccarat, and video poker. Blackjack boasts a low house edge, especially with optimal strategy, while baccarat offers favorable odds on banker bets. Video poker, particularly Jacks or Better, can yield high returns when played with the right strategy. Additionally, some slot machines feature progressive jackpots that can offer substantial payouts, though they come with higher volatility. Overall, understanding the odds and strategies behind these games can significantly enhance a player's chances of winning.