Yes, you can use a credit card at many casinos, but policies vary by location. Some casinos allow credit card transactions for gaming chips or slot machines, while others may restrict their use due to regulations or potential gambling addiction concerns. Additionally, cash advances from credit cards are often available at ATMs within casinos, though they typically come with high fees and interest rates. It's essential to check the specific casino's rules and consider the financial implications before using a credit card for gambling.