As NFL Week 5 approaches, savvy bettors should consider key matchups that could yield profitable outcomes. Look for opportunities in games featuring strong home teams, like the Kansas City Chiefs, who often dominate at Arrowhead Stadium. Additionally, betting on the over/under in high-scoring matchups, such as the Miami Dolphins versus the Los Angeles Chargers, could be wise. Keep an eye on injury reports and team trends, as they can significantly impact spreads and totals. With careful analysis, Week 5 presents exciting betting prospects for both seasoned and novice gamblers.