The best way to win at blackjack is to understand and apply basic strategy, which involves knowing when to hit, stand, double down, or split based on your hand and the dealer's upcard. Additionally, managing your bankroll effectively and setting limits can help minimize losses. Card counting, while challenging, can also provide an edge by tracking the ratio of high to low cards remaining in the deck. Always remember to play responsibly and enjoy the game, as luck plays a significant role in the outcome.