NFL picks straight up refer to predictions made on the outcome of games without considering point spreads. Fans and analysts alike engage in this practice to showcase their knowledge of teams, players, and matchups. Each week, enthusiasts evaluate factors such as team performance, injuries, and historical trends to make informed choices. Straight-up picks can add excitement to the viewing experience, as fans root for their selected teams to secure victories. Whether for friendly competitions or serious betting, making straight-up picks is a popular way to engage with the NFL season.